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Thursday, 29 October 2026
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Targeted drug slows progression of advanced breast cancer in trial

A phase three clinical trial published in JAMA shows the drug trastuzumab rezetecan significantly lowers the risk of cancer progression compared with chemotherapy.

FTMQ News, written by our newsroom0 views

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Picture: Fox News

A phase three clinical trial called HORIZON-Breast06 found that the targeted drug trastuzumab rezetecan reduced the risk of cancer progression or death by 73 percent compared with standard chemotherapy, Fox News reported. The study was published in the Journal of the American Medical Association. [1]

Fox News reported that researchers evaluated 551 female patients with ERBB2-low metastatic breast cancer. This type of cancer features low levels of HER2, a protein that can promote the growth of cancer cells. [1]

Targeted therapy, including monoclonal antibodies and small-molecule drugs, is part of a broad range of cancer treatments that also includes surgery, chemotherapy, radiation therapy, and immunotherapy. As FTMQ News reported earlier, additional screening methods such as ultrasounds are often required to detect tumors that standard mammograms miss in dense breast tissue. [3][4]

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In short

  • Trastuzumab rezetecan linked to a 73 percent lower risk of cancer progression or death compared to chemotherapy.
  • The HORIZON-Breast06 phase three trial analyzed 551 female patients with ERBB2-low metastatic breast cancer.
  • HER2 is a protein that can help cancer cells grow.

Sources

Every paragraph above points to the numbered items it rests on. Read the originals here.

  1. [1]Targeted drug shrinks tumors in 3 out of 4 patients with advanced breast cancerFox News, 1h ago (the report this story comes from)
  2. [2]IKEA bets on city store format, targets 3-4 more stores in BengaluruDeccan Herald, 4h ago

Background

  1. [3]Cancer treatment on Wikipedia
  2. [4]Dense breast tissue increases risk of missed tumors during mammograms FTMQ News, 6d ago
  3. [5]Minority groups in England less likely to receive routine breast screening FTMQ News, 4d ago

Our newsroom writes these reports with the help of software, from the 5 sources listed and nothing else, and checks them against those sources. Facts can still be wrong or move on; the originals are the record. Spotted a mistake? Write to daniel@monsterkong.com.

Earlier reports of ours on the same people and subjects.

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